Predictors of Adverse Events and Determinants of the Voriconazole Trough Concentration in Kidney Transplantation Recipients

• Main Authors: Yi‐Chang Zhao (Author), Xiao‐Bin Lin (Author), Bi‐Kui Zhang (Author), Yi‐wen Xiao (Author), Ping Xu (Author), Feng Wang (Author), Da‐Xiong Xiang (Author), Xu‐Biao Xie (Author), Feng‐Hua Peng (Author), Miao Yan (Author)
• Format: Book
• Published: Wiley, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Voriconazole is the mainstay for the treatment of invasive fungal infections in patients who underwent a kidney transplant. Variant CYP2C19 alleles, hepatic function, and concomitant medications are directly involved in the metabolism of voriconazole. However, the drug is also associated with numero...