Improved radiolabeling of DOTATOC with trivalent radiometals for clinical application by addition of ethanol

• Main Authors: Elisabeth Eppard (Author), Marylaine Pèrez-Malo (Author), Frank Rösch (Author)
• 格式: 图书
• 出版: SpringerOpen, 2016-04-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Abstract Background Typically, metal-based radiopharmaceuticals are synthesized in aqueous solutions with no or low ethanol content. Labeling yields are defined by temperature, period of labeling, amount of precursor, pH etc. As recently observed, radiolabeling yields (RCY) seem to increase in the p...