Involvement of GABAA Receptors in the Neuroprotective Effect of Theanine on Focal Cerebral Ischemia in Mice

• Main Authors: Nobuaki Egashira (Author), Kazuhide Hayakawa (Author), Megumi Osajima (Author), Kenichi Mishima (Author), Katsunori Iwasaki (Author), Ryozo Oishi (Author), Michihiro Fujiwara (Author)
• Format: Book
• Published: Elsevier, 2007-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We investigated the involvement of γ-aminobutyric acidA (GABAA) receptors in the neuroprotective effect of γ-glutamylethylamide (theanine), a component of Japanese green tea, following a 4-h middle cerebral artery (MCA) occlusion in mice. Theanine (1 mg/kg) reduced the size of the cerebral infarct a...