Reversal of metabolic disorders by pharmacological activation of bile acid receptors TGR5 and FXR

• Main Authors: Kavita Jadhav (Author), Yang Xu (Author), Yanyong Xu (Author), Yuanyuan Li (Author), Jiesi Xu (Author), Yingdong Zhu (Author), Luciano Adorini (Author), Yoon Kwang Lee (Author), Takhar Kasumov (Author), Liya Yin (Author), Yanqiao Zhang (Author)
• Format: Book
• Published: Elsevier, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Activation of the bile acid (BA) receptors farnesoid X receptor (FXR) or G protein-coupled bile acid receptor (GPBAR1; TGR5) improves metabolic homeostasis. In this study, we aim to determine the impact of pharmacological activation of bile acid receptors by INT-767 on reversal of diet-i...