Novel [(N-alkyl-3-indolylmethylene)hydrazono]oxindoles arrest cell cycle and induce cell apoptosis by inhibiting CDK2 and Bcl-2: synthesis, biological evaluation and in silico studies
As a continuation for our previous work, a novel set of N-alkylindole-isatin conjugates (7, 8a-c, 9 and 10a-e) is here designed and synthesised with the prime aim to develop more efficient isatin-based antitumor candidates. Utilising the SAR outputs from the previous study, our design here is based...
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Principais autores: | , , , , , , , , , |
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Formato: | Livro |
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Taylor & Francis Group,
2020-01-01T00:00:00Z.
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Número de Chamada: |
A1234.567 |
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Cópia 1 | Disponível |