NOD2 receptor is crucial for protecting against the digestive form of Chagas disease.

• Main Authors: Nathalie de Sena Pereira (Author), Tamyres Bernadete Dantas Queiroga (Author), Denis Dantas da Silva (Author), Manuela Sales Lima Nascimento (Author), Cléber Mesquita de Andrade (Author), Janeusa Trindade de Souto (Author), Mayra Fernanda Ricci (Author), Rosa Maria Esteves Arantes (Author), Dario Simões Zamboni (Author), Egler Chiari (Author), Antônia Cláudia Jácome da Câmara (Author), Lúcia Maria da Cunha Galvão (Author), Paulo Marcos Matta Guedes (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Digestive and cardiodigestive forms of Chagas' disease are observed in 2% to 27% of the patients, depending on their geographic location, Trypanosoma cruzi strain and immunopathological responses. The aim of this work was to evaluate the role of NOD2 innate immune receptor in the pathogenesis o...