Self-Dissolving Microneedle Arrays for Transdermal Absorption Enhancement of Human Parathyroid Hormone (1-34)

• Main Authors: Chihiro Naito (Author), Hidemasa Katsumi (Author), Tomoko Suzuki (Author), Ying-shu Quan (Author), Fumio Kamiyama (Author), Toshiyasu Sakane (Author), Akira Yamamoto (Author)
• Format: Book
• Published: MDPI AG, 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Human parathyroid hormone (1-34) (PTH) has been widely used as the subcutaneous injection formulation for the treatment of osteoporosis. In the present study, we developed an efficient transdermal delivery system of PTH by using dissolving microneedle arrays (MNs) composed of hyaluronic acid (HA) fo...