Interleukin-33 Ameliorates Murine Systemic Lupus Erythematosus and Is Associated with Induction of M2 Macrophage Polarisation and Regulatory T Cells

• Main Authors: Mo Yin Mok (Author), Ka Sin Law (Author), Wing Yin Kong (Author), Cai Yun Luo (Author), Endale T. Asfaw (Author), Kwok Wah Chan (Author), Fang Ping Huang (Author), Chak Sing Lau (Author), Godfrey Chi Fung Chan (Author)
• Format: Book
• Published: Karger Publishers, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The innate cytokine IL-33 is increasingly recognised to possess biological effects on various immune cells. We have previously demonstrated elevated serum level of soluble ST2 in patients with active systemic lupus erythematosus suggesting involvement of IL-33 and its receptor in the lupus pathogene...