[6]-Shogaol Attenuates Oxaliplatin-Induced Allodynia through Serotonergic Receptors and GABA in the Spinal Cord in Mice

• Main Authors: Suyong Kim (Author), Juan Gang (Author), Ji-Hwan Lee (Author), Hyejin Yang (Author), Chunhoo Cheon (Author), Seong-Gyu Ko (Author), Hyunsu Bae (Author), Woojin Kim (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although oxaliplatin is a well-known anti-cancer agent used for the treatment of colorectal cancer, treated patients often experience acute cold and mechanical allodynia as side effects. Unfortunately, no optimal treatment has been developed yet. In this study, [6]-shogaol (10 mg/kg, i.p.), which is...