BMSC-Derived Exosomes Alleviate Intervertebral Disc Degeneration by Modulating AKT/mTOR-Mediated Autophagy of Nucleus Pulposus Cells

• المؤلفون الرئيسيون: Quan Xiao (مؤلف), Zhe Zhao (مؤلف), Yun Teng (مؤلف), Lungang Wu (مؤلف), Jinlong Wang (مؤلف), Hongjun Xu (مؤلف), Sumei Chen (مؤلف), Quan Zhou (مؤلف)
• التنسيق: كتاب
• منشور في: Hindawi Limited, 2022-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

The pathogenesis of intervertebral disc degeneration (IDD) is still unclear. It has been shown that the pathological process of IDD is most closely related to inflammation of nucleus pulposus cells (NPCs), in which inflammatory factors play an important role. Exosomes are the main paracrine mediator...