BMSC-Derived Exosomes Alleviate Intervertebral Disc Degeneration by Modulating AKT/mTOR-Mediated Autophagy of Nucleus Pulposus Cells

BMSC-Derived Exosomes Alleviate Intervertebral Disc Degeneration by Modulating AKT/mTOR-Mediated Autophagy of Nucleus Pulposus Cells

The pathogenesis of intervertebral disc degeneration (IDD) is still unclear. It has been shown that the pathological process of IDD is most closely related to inflammation of nucleus pulposus cells (NPCs), in which inflammatory factors play an important role. Exosomes are the main paracrine mediator...

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Main Authors: Quan Xiao (Author), Zhe Zhao (Author), Yun Teng (Author), Lungang Wu (Author), Jinlong Wang (Author), Hongjun Xu (Author), Sumei Chen (Author), Quan Zhou (Author)
Format: Book
Published: Hindawi Limited, 2022-01-01T00:00:00Z.
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