Hepatic Insulin Resistance in Hyperthyroid Rat Liver: Vitamin E Supplementation Highlights a Possible Role of ROS

• Main Authors: Gianluca Fasciolo (Author), Gaetana Napolitano (Author), Marianna Aprile (Author), Simona Cataldi (Author), Valerio Costa (Author), Alfredo Ciccodicola (Author), Sergio Di Meo (Author), Paola Venditti (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Thyroid hormones are normally involved in glycaemic control, but their excess can lead to altered glucose metabolism and insulin resistance (IR). Since hyperthyroidism-linked increase in ROS results in tissue oxidative stress that is considered a hallmark of conditions leading to IR, it is conceivab...