Regulatory network analysis reveals the oncogenesis roles of feed-forward loops and therapeutic target in T-cell acute lymphoblastic leukemia

• Autors principals: Mengxuan Xia (Autor), Qiong Zhang (Autor), Mei Luo (Autor), Pan Li (Autor), Yingxue Wang (Autor), Qian Lei (Autor), An-Yuan Guo (Autor)
• Format: Llibre
• Publicat: BMC, 2019-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Abstract Background T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy. Aberrant expressed genes contribute to the development and progression of T-ALL. However, the regulation underlying their aberrant expression remains elusive. Dysregulated expression of transcr...