The Interaction between Adult Cardiac Fibroblasts and Embryonic Stem Cell-Derived Cardiomyocytes Leads to Proarrhythmic Changes in In Vitro Cocultures

• Main Authors: Jan Trieschmann (Author), Daniel Bettin (Author), Moritz Haustein (Author), Annette Köster (Author), Marek Molcanyi (Author), Marcel Halbach (Author), Mira Hanna (Author), Mariam Fouad (Author), Konrad Brockmeier (Author), Jürgen Hescheler (Author), Kurt Pfannkuche (Author), Tobias Hannes (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Transplantation of stem cell-derived cardiomyocytes is one of the most promising therapeutic approaches after myocardial infarction, as loss of cardiomyocytes is virtually irreversible by endogenous repair mechanisms. In myocardial scars, transplanted cardiomyocytes will be in immediate contact with...