Hyperglycemia Impairs Acetylcholine-Induced Vasodilation of Retinal Arterioles Through Polyol Pathway-Independent Mechanisms in Rats

• Main Authors: Asami Mori (Author), Orie Saigo (Author), Kenji Sakamoto (Author), Tsutomu Nakahara (Author), Kunio Ishii (Author)
• פורמט: ספר
• יצא לאור: Elsevier, 2010-01-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

We previously reported that acetylcholine (ACh)-induced vasodilation of retinal arterioles is diminished in diabetic rats; however, the underlying mechanism(s) of this phenomenon has not been fully elucidated. To determine the role of the polyol pathway in the diabetes-induced retinal vascular dysfu...