Aggressive Periodontitis: A case report with exome sequencing and functional characterization of identified variant

• Main Authors: Waheed Awotoye (Author), Patricia Ayanbadejo (Author), Steven Eliason (Author), Kehinde Umeizudike (Author), Ayodele Ogundana (Author), Dan Su (Author), Tadkamol Krongbaramee (Author), Emmanuel Aladenika (Author), Azeez Alade (Author), Abimbola Oladayo (Author), Abdul-Warith Akinshipo (Author), Tamara Busch (Author), Wasiu Adeyemo (Author), Brad Amendt (Author), Azeez Butali (Author)
• Format: Book
• Published: Nigerian Dental Association, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aggressive periodontitis (AgP) is characterized by rapid and progressive destruction of the periodontal tissues and eventual tooth loss. Genetic risk contributions have been explored and rare mutations in NOD2 were reported. Sequencing analysis of the coding regions of NOD2 was conducted using indiv...