Evaluation of salivary tumor necrosis factor α as a diagnostic biomarker in oral submucosal fibrosis and squamous cell carcinoma of the oral cavity and oropharynx: a cross sectional observational study

• Main Authors: Sabiha Abdul Aziz Shaikh (Author), Ceena Denny E (Author), Reshma Kumarchandra (Author), Srikant Natarajan (Author), Johan Sunny (Author), Nandita Shenoy (Author), Nandita K. P (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IntroductionTumor necrosis factor α (TNF-α) is known to be associated with chronic inflammation, and its expression has been shown to increase in advanced cancers. Chronic inflammation is a characteristic feature of oral submucous fibrosis (OSMF), which is a potentially malignant disorder (PMD). Squ...