Effects of Interleukin-1β in Glycinergic Transmission at the Central Amygdala

• Main Authors: Jocelyn Solorza (Author), Carolina A. Oliva (Author), Karen Castillo (Author), Gabriela Amestica (Author), María Constanza Maldifassi (Author), Xaviera A. López-Cortés (Author), Rafael Barra (Author), Jimmy Stehberg (Author), Matthias Piesche (Author), Patricio Sáez-Briones (Author), Wendy González (Author), Mauricio Arenas-Salinas (Author), Trinidad A. Mariqueo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Interleukin-1β (IL-1β) is an important cytokine that modulates peripheral and central pain sensitization at the spinal level. Among its effects, it increases spinal cord excitability by reducing inhibitory Glycinergic and GABAergic neurotransmission. In the brain, IL-1β is released by glial cells in...