Knockdown of PTGS2 by CRISPR/CAS9 System Designates a New Potential Gene Target for Melanoma Treatment

• المؤلفون الرئيسيون: Giuseppe Ercolano (مؤلف), Paola De Cicco (مؤلف), Valentina Rubino (مؤلف), Giuseppe Terrazzano (مؤلف), Giuseppina Ruggiero (مؤلف), Roberta Carriero (مؤلف), Paolo Kunderfranco (مؤلف), Angela Ianaro (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

CRISPR/Cas9 has become a powerful method to engineer genomes and to activate or to repress genes expression. As such, in cancer research CRISPR/Cas9 technology represents an efficient tool to dissect mechanisms of tumorigenesis and to discover novel targets for drug development. Here, we employed th...