Knockdown of PTGS2 by CRISPR/CAS9 System Designates a New Potential Gene Target for Melanoma Treatment

• প্রধান লেখক: Giuseppe Ercolano (লেখক), Paola De Cicco (লেখক), Valentina Rubino (লেখক), Giuseppe Terrazzano (লেখক), Giuseppina Ruggiero (লেখক), Roberta Carriero (লেখক), Paolo Kunderfranco (লেখক), Angela Ianaro (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

CRISPR/Cas9 has become a powerful method to engineer genomes and to activate or to repress genes expression. As such, in cancer research CRISPR/Cas9 technology represents an efficient tool to dissect mechanisms of tumorigenesis and to discover novel targets for drug development. Here, we employed th...