Knockdown of PTGS2 by CRISPR/CAS9 System Designates a New Potential Gene Target for Melanoma Treatment

• Prif Awduron: Giuseppe Ercolano (Awdur), Paola De Cicco (Awdur), Valentina Rubino (Awdur), Giuseppe Terrazzano (Awdur), Giuseppina Ruggiero (Awdur), Roberta Carriero (Awdur), Paolo Kunderfranco (Awdur), Angela Ianaro (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

CRISPR/Cas9 has become a powerful method to engineer genomes and to activate or to repress genes expression. As such, in cancer research CRISPR/Cas9 technology represents an efficient tool to dissect mechanisms of tumorigenesis and to discover novel targets for drug development. Here, we employed th...