Knockdown of PTGS2 by CRISPR/CAS9 System Designates a New Potential Gene Target for Melanoma Treatment

• Κύριοι συγγραφείς: Giuseppe Ercolano (Συγγραφέας), Paola De Cicco (Συγγραφέας), Valentina Rubino (Συγγραφέας), Giuseppe Terrazzano (Συγγραφέας), Giuseppina Ruggiero (Συγγραφέας), Roberta Carriero (Συγγραφέας), Paolo Kunderfranco (Συγγραφέας), Angela Ianaro (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

CRISPR/Cas9 has become a powerful method to engineer genomes and to activate or to repress genes expression. As such, in cancer research CRISPR/Cas9 technology represents an efficient tool to dissect mechanisms of tumorigenesis and to discover novel targets for drug development. Here, we employed th...