Knockdown of PTGS2 by CRISPR/CAS9 System Designates a New Potential Gene Target for Melanoma Treatment

• Príomhchruthaitheoirí: Giuseppe Ercolano (Údar), Paola De Cicco (Údar), Valentina Rubino (Údar), Giuseppe Terrazzano (Údar), Giuseppina Ruggiero (Údar), Roberta Carriero (Údar), Paolo Kunderfranco (Údar), Angela Ianaro (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

CRISPR/Cas9 has become a powerful method to engineer genomes and to activate or to repress genes expression. As such, in cancer research CRISPR/Cas9 technology represents an efficient tool to dissect mechanisms of tumorigenesis and to discover novel targets for drug development. Here, we employed th...