Knockdown of PTGS2 by CRISPR/CAS9 System Designates a New Potential Gene Target for Melanoma Treatment

• मुख्य लेखकों: Giuseppe Ercolano (लेखक), Paola De Cicco (लेखक), Valentina Rubino (लेखक), Giuseppe Terrazzano (लेखक), Giuseppina Ruggiero (लेखक), Roberta Carriero (लेखक), Paolo Kunderfranco (लेखक), Angela Ianaro (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

CRISPR/Cas9 has become a powerful method to engineer genomes and to activate or to repress genes expression. As such, in cancer research CRISPR/Cas9 technology represents an efficient tool to dissect mechanisms of tumorigenesis and to discover novel targets for drug development. Here, we employed th...