Knockdown of PTGS2 by CRISPR/CAS9 System Designates a New Potential Gene Target for Melanoma Treatment

• 主要な著者: Giuseppe Ercolano (著者), Paola De Cicco (著者), Valentina Rubino (著者), Giuseppe Terrazzano (著者), Giuseppina Ruggiero (著者), Roberta Carriero (著者), Paolo Kunderfranco (著者), Angela Ianaro (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

CRISPR/Cas9 has become a powerful method to engineer genomes and to activate or to repress genes expression. As such, in cancer research CRISPR/Cas9 technology represents an efficient tool to dissect mechanisms of tumorigenesis and to discover novel targets for drug development. Here, we employed th...