Knockdown of PTGS2 by CRISPR/CAS9 System Designates a New Potential Gene Target for Melanoma Treatment

• Үндсэн зохиолчид: Giuseppe Ercolano (Зохиогч), Paola De Cicco (Зохиогч), Valentina Rubino (Зохиогч), Giuseppe Terrazzano (Зохиогч), Giuseppina Ruggiero (Зохиогч), Roberta Carriero (Зохиогч), Paolo Kunderfranco (Зохиогч), Angela Ianaro (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

CRISPR/Cas9 has become a powerful method to engineer genomes and to activate or to repress genes expression. As such, in cancer research CRISPR/Cas9 technology represents an efficient tool to dissect mechanisms of tumorigenesis and to discover novel targets for drug development. Here, we employed th...