Knockdown of PTGS2 by CRISPR/CAS9 System Designates a New Potential Gene Target for Melanoma Treatment

• Главные авторы: Giuseppe Ercolano (Автор), Paola De Cicco (Автор), Valentina Rubino (Автор), Giuseppe Terrazzano (Автор), Giuseppina Ruggiero (Автор), Roberta Carriero (Автор), Paolo Kunderfranco (Автор), Angela Ianaro (Автор)
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• Опубликовано: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• Предметы: article
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CRISPR/Cas9 has become a powerful method to engineer genomes and to activate or to repress genes expression. As such, in cancer research CRISPR/Cas9 technology represents an efficient tool to dissect mechanisms of tumorigenesis and to discover novel targets for drug development. Here, we employed th...