Knockdown of PTGS2 by CRISPR/CAS9 System Designates a New Potential Gene Target for Melanoma Treatment

• Asıl Yazarlar: Giuseppe Ercolano (Yazar), Paola De Cicco (Yazar), Valentina Rubino (Yazar), Giuseppe Terrazzano (Yazar), Giuseppina Ruggiero (Yazar), Roberta Carriero (Yazar), Paolo Kunderfranco (Yazar), Angela Ianaro (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

CRISPR/Cas9 has become a powerful method to engineer genomes and to activate or to repress genes expression. As such, in cancer research CRISPR/Cas9 technology represents an efficient tool to dissect mechanisms of tumorigenesis and to discover novel targets for drug development. Here, we employed th...