Knockdown of PTGS2 by CRISPR/CAS9 System Designates a New Potential Gene Target for Melanoma Treatment

• Автори: Giuseppe Ercolano (Автор), Paola De Cicco (Автор), Valentina Rubino (Автор), Giuseppe Terrazzano (Автор), Giuseppina Ruggiero (Автор), Roberta Carriero (Автор), Paolo Kunderfranco (Автор), Angela Ianaro (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

CRISPR/Cas9 has become a powerful method to engineer genomes and to activate or to repress genes expression. As such, in cancer research CRISPR/Cas9 technology represents an efficient tool to dissect mechanisms of tumorigenesis and to discover novel targets for drug development. Here, we employed th...