Berberine Ameliorates Diabetes-Associated Cognitive Decline through Modulation of Aberrant Inflammation Response and Insulin Signaling Pathway in DM Rats

• Main Authors: Qingjie Chen (Author), Ran Mo (Author), Ninghua Wu (Author), Xin Zou (Author), Cai Shi (Author), Jing Gong (Author), Jingbin Li (Author), Ke Fang (Author), Dingkun Wang (Author), Deshen Yang (Author), Kaifu Wang (Author), Juan Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Memory-impairment was one of the common characteristics in patients with diabetes mellitus. The release of chronic inflammation mediators and insulin resistance in diabetic brain gave rise to the generation of toxic factor Aβ42 which was the marker of Alzheimer's disease. In additio...