Differential action of pro-angiogenic and anti-angiogenic components of Danhong injection in ischemic vascular disease or tumor models

• Main Authors: Shuang He (Author), Rongrong Chen (Author), Li Peng (Author), Zhenzuo Jiang (Author), Haixin Liu (Author), Zihao Chen (Author), Tiechan Zhao (Author), John Owoicho Orgah (Author), Jie Ren (Author), Peng Zhang (Author), Yuefei Wang (Author), Xiumei Gao (Author), Yan Zhu (Author)
• Format: Book
• Published: BMC, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Objective We investigate the chemical basis and mechanism of angiogenesis regulation by a multicomponent Chinese medicine Danhong injection (DHI). Methods DHI was fractionated and screened for angiogenesis activities by in vitro tube formation and migration assays. The composition of DHI co...