CD161 Expression on Mucosa-Associated Invariant T Cells is Reduced in HIV-Infected Subjects Undergoing Antiretroviral Therapy Who Do Not Recover CD4+ T Cells

• Main Authors: Michael L Freeman (Author), Stephen R. Morris (Author), Michael M. Lederman (Author)
• 格式: 圖書
• 出版: Case Western Reserve University, 2017-08-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Background: Mucosa-associated invariant T (MAIT) cells are a recently identified class of innate-like T cells that are involved in the mucosal immune response. MAIT cells are characterized by expression of TCR Va7.2 and CD161. In HIV infection, there is a profound early loss of MAIT cells from the c...