Cell-Cycle-Dependent Regulation of Ca2+-Activated K+ Channel in Jurkat T-Lymphocyte

• Main Authors: Takashi Morimoto (Author), Susumu Ohya (Author), Hidetoshi Hayashi (Author), Kikuo Onozaki (Author), Yuji Imaizumi (Author)
• Format: Book
• Published: Elsevier, 2007-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Small-conductance Ca2+-activated K+ (SK2) channel plays an important role in the activation of Jurkat T-lymphocytes by maintaining electrical gradients for the sustained Ca2+ influx. Apamin-sensitive K+ current was significantly decreased with cell-cycle progression from G0/G1 into G2/M phases, and...