Preservation of vascular endothelial glycocalyx and barrier by activation of adenosine A2A receptor (A2AR) improved renal dysfunction in cirrhotic rats

• Päätekijät: Chia-Chang Huang (Tekijä), Hsiao-Chin Shen (Tekijä), Roger Lin (Tekijä), Ying-Ying Yang (Tekijä), Yun-Chien Chang (Tekijä), Tsai-Ling Liao (Tekijä), Shiang-Fen Huang (Tekijä), Han-Chieh Lin (Tekijä), Ming-Chih Hou (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Elsevier, 2023-05-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Cirrhosis-related hepatic and renal endothelial dysfunction is characterized by macrophage-endothelium adhesion-mediated inflammation, glycocalyx/barrier damage, and impaired vasodilation. Activation of adenosine A2A receptor (A2AR) protects cirrhotic rats from impairment of hepatic microcirculation...