Boswellic acid sensitizes gastric cancer cells to Cisplatin-induced apoptosis via p53-mediated pathway

• Main Authors: Shadia Al-Bahlani (Author), Ikram A. Burney (Author), Buthaina Al-Dhahli (Author), Safiya Al-Kharusi (Author), Fakhra Al-Kharousi (Author), Amani Al-Kalbani (Author), Ikhlas Ahmed (Author)
• Format: Book
• Published: BMC, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cisplatin (CDDP) is an effective anticancer drug for Gastric cancer (GC) that induces apoptosis by altering pro- (p53) and anti-apoptotic (Akt and NFkB) proteins; however, chemoresistance remains a big challenge. Additional compounds with promising anticancer effects such as AKBA...