Boswellic acid sensitizes gastric cancer cells to Cisplatin-induced apoptosis via p53-mediated pathway

• Главные авторы: Shadia Al-Bahlani (Автор), Ikram A. Burney (Автор), Buthaina Al-Dhahli (Автор), Safiya Al-Kharusi (Автор), Fakhra Al-Kharousi (Автор), Amani Al-Kalbani (Автор), Ikhlas Ahmed (Автор)
• Формат: ‌
• Опубликовано: BMC, 2020-09-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Abstract Background Cisplatin (CDDP) is an effective anticancer drug for Gastric cancer (GC) that induces apoptosis by altering pro- (p53) and anti-apoptotic (Akt and NFkB) proteins; however, chemoresistance remains a big challenge. Additional compounds with promising anticancer effects such as AKBA...