Overcoming the Drawbacks of Sulpiride by Means of New Crystal Forms

• Príomhchruthaitheoirí: Rebecca Birolo (Údar), Federica Bravetti (Údar), Simone Bordignon (Údar), Ilenia D'Abbrunzo (Údar), Paolo P. Mazzeo (Údar), Beatrice Perissutti (Údar), Alessia Bacchi (Údar), Michele R. Chierotti (Údar), Roberto Gobetto (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: MDPI AG, 2022-08-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

This study aims at developing new multicomponent crystal forms of sulpiride, an antipsychotic drug. The main goal was to improve its solubility since it belongs to class IV of the BCS. Nine new adducts were obtained by combining the active pharmaceutical ingredient with acid coformers: a salt cocrys...