Discovery of a new mitochondria permeability transition pore (mPTP) inhibitor based on gallic acid

• Main Authors: José Teixeira (Author), Catarina Oliveira (Author), Fernando Cagide (Author), Ricardo Amorim (Author), Jorge Garrido (Author), Fernanda Borges (Author), Paulo J. Oliveira (Author)
• 格式: 圖書
• 出版: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Pharmacological interventions targeting mitochondria present several barriers for a complete efficacy. Therefore, a new mitochondriotropic antioxidant (AntiOxBEN3) based on the dietary antioxidant gallic acid was developed. AntiOxBEN3 accumulated several thousand-fold inside isolated rat liver mitoc...