Integrated lipidomic and transcriptomic analyses identify altered nerve triglycerides in mouse models of prediabetes and type 2 diabetes

• Main Authors: Phillipe D. O'Brien (Author), Kai Guo (Author), Stephanie A. Eid (Author), Amy E. Rumora (Author), Lucy M. Hinder (Author), John M. Hayes (Author), Faye E. Mendelson (Author), Junguk Hur (Author), Eva L. Feldman (Author), Annemieke Aartsma-Rus (Author), James Dowling (Author), Maaike van Putten (Author)
• Format: Book
• Published: The Company of Biologists, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Peripheral neuropathy (PN) is a complication of prediabetes and type 2 diabetes (T2D). Increasing evidence suggests that factors besides hyperglycaemia contribute to PN development, including dyslipidaemia. The objective of this study was to determine differential lipid classes and altered gene expr...