Reduced nuclear DNA methylation and mitochondrial transcript changes in adenomas do not associate with mtDNA methylation

Abstract Background Altered mitochondrial function and large-scale changes to DNA methylation patterns in the nuclear genome are both hallmarks of colorectal cancer (CRC). Mitochondria have multiple copies of a 16 kb circular genome that contains genes that are vital for their function. While DNA me...

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Bibliographic Details
Main Authors: M. J. Morris (Author), L. B. Hesson (Author), R. C. Poulos (Author), R. L. Ward (Author), J. W. H. Wong (Author), N. A. Youngson (Author)
Format: Book
Published: BMC, 2018-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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