The Cancer Drug Fraction of Metabolism Database

• Main Authors: Liyan Hua (Author), Chien‐Wei Chiang (Author), Wang Cong (Author), Jin Li (Author), Xueying Wang (Author), Lijun Cheng (Author), Weixing Feng (Author), Sara K. Quinney (Author), Lei Wang (Author), Lang Li (Author)
• Format: Book
• Published: Wiley, 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study aims to create a database for quantifying the fraction of metabolism of cytochrome P450 isozymes for cancer drugs approved by the US Food and Drug Administration. A reproducible data collection protocol was developed to extract essential information, including both substrate‐depletion and...