Unraveling Gene Fusions for Drug Repositioning in High-Risk Neuroblastoma

• Main Authors: Zhichao Liu (Author), Xi Chen (Author), Ruth Roberts (Author), Ruili Huang (Author), Mike Mikailov (Author), Weida Tong (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

High-risk neuroblastoma (NB) remains a significant therapeutic challenge facing current pediatric oncology patients. Structural variants such as gene fusions have shown an initial promise in enhancing mechanistic understanding of NB and improving survival rates. In this study, we performed a compreh...