PRMT5 Prevents Cardiomyocyte Hypertrophy via Symmetric Dimethylating HoxA9 and Repressing HoxA9 Expression

• Váldodahkkit: Sidong Cai (Dahkki), Rong Liu (Dahkki), Panxia Wang (Dahkki), Jingyan Li (Dahkki), Tingting Xie (Dahkki), Minghui Wang (Dahkki), Yanjun Cao (Dahkki), Zhuoming Li (Dahkki), Peiqing Liu (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The present study reveals a link between protein arginine methyltransferase 5 (PRMT5) and Homebox A9 (HoxA9) in the regulation of cardiomyocyte hypertrophy. In cardiomyocyte hypertrophy induced by β-adrenergic receptor agonist isoprenaline (ISO), PRMT5 expression was decreased while HoxA9 was upregu...