PRMT5 Prevents Cardiomyocyte Hypertrophy via Symmetric Dimethylating HoxA9 and Repressing HoxA9 Expression

• Asıl Yazarlar: Sidong Cai (Yazar), Rong Liu (Yazar), Panxia Wang (Yazar), Jingyan Li (Yazar), Tingting Xie (Yazar), Minghui Wang (Yazar), Yanjun Cao (Yazar), Zhuoming Li (Yazar), Peiqing Liu (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The present study reveals a link between protein arginine methyltransferase 5 (PRMT5) and Homebox A9 (HoxA9) in the regulation of cardiomyocyte hypertrophy. In cardiomyocyte hypertrophy induced by β-adrenergic receptor agonist isoprenaline (ISO), PRMT5 expression was decreased while HoxA9 was upregu...