Flexible, AAV-equipped Genetic Modules for Inducible Control of Gene Expression in Mammalian Brain

• Główni autorzy: Godwin K Dogbevia (Autor), Martin Roβmanith (Autor), Rolf Sprengel (Autor), Mazahir T Hasan (Autor)
• Format: Książka
• Wydane: Elsevier, 2016-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Controlling gene expression in mammalian brain is of utmost importance to causally link the role of gene function to cell circuit dynamics under normal conditions and disease states. We have developed recombinant adeno-associated viruses equipped with tetracycline-controlled genetic switches for ind...