Functional characterization of two enhancers located downstream FOXP2

• Principais autores: Raúl Torres-Ruiz (Autor), Antonio Benítez-Burraco (Autor), Marta Martínez-Lage (Autor), Sandra Rodríguez-Perales (Autor), Paloma García-Bellido (Autor)
• Formato: Livro
• Publicado em: BMC, 2019-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background Mutations in the coding region of FOXP2 are known to cause speech and language impairment. However, it is not clear how dysregulation of the gene contributes to language deficit. Interestingly, microdeletions of the region downstream the gene have been associated with cognitive d...