The Role of Carvedilol in the Treatment of Dilated and Anthracyclines-Induced Cardiomyopathy

• Main Authors: Makoto Kodama (Author), Kenji Suzuki (Author), Somasundaram Arumugam (Author), Rajarajan A. Thandavarayan (Author), Kenichi Watanabe (Author), Wawaimuli Arozal (Author), Flori R. Sari (Author)
• Format: Book
• Published: MDPI AG, 2011-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although chronic sympathetic activation provides inotropic and chronotropic support to the failing heart, such activation may also have deleterious effects, including the direct cardiotoxic effects of catecholamines, activation of the renin-angiotensin-aldosterone system and an increase in myocardia...