Antiproliferative and Tubulin-Destabilising Effects of 3-(Prop-1-en-2-yl)azetidin-2-Ones and Related Compounds in MCF-7 and MDA-MB-231 Breast Cancer Cells

A series of novel 3-(prop-1-en-2-yl)azetidin-2-one, 3-allylazetidin-2-one and 3-(buta-1,3-dien-1-yl)azetidin-2-one analogues of combretastatin A-4 (CA-4) were designed and synthesised as colchicine-binding site inhibitors (CBSI) in which the ethylene bridge of CA-4 was replaced with a β-lactam (2-az...

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ग्रंथसूची विवरण
मुख्य लेखकों: Shu Wang (लेखक), Azizah M. Malebari (लेखक), Thomas F. Greene (लेखक), Shubhangi Kandwal (लेखक), Darren Fayne (लेखक), Seema M. Nathwani (लेखक), Daniela M. Zisterer (लेखक), Brendan Twamley (लेखक), Niamh M. O'Boyle (लेखक), Mary J. Meegan (लेखक)
स्वरूप: पुस्तक
प्रकाशित: MDPI AG, 2023-07-01T00:00:00Z.
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3rd Floor Main Library

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