Antiproliferative and Tubulin-Destabilising Effects of 3-(Prop-1-en-2-yl)azetidin-2-Ones and Related Compounds in MCF-7 and MDA-MB-231 Breast Cancer Cells
A series of novel 3-(prop-1-en-2-yl)azetidin-2-one, 3-allylazetidin-2-one and 3-(buta-1,3-dien-1-yl)azetidin-2-one analogues of combretastatin A-4 (CA-4) were designed and synthesised as colchicine-binding site inhibitors (CBSI) in which the ethylene bridge of CA-4 was replaced with a β-lactam (2-az...
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मुख्य लेखकों: | , , , , , , , , , |
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स्वरूप: | पुस्तक |
प्रकाशित: |
MDPI AG,
2023-07-01T00:00:00Z.
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विषय: | |
ऑनलाइन पहुंच: | Connect to this object online. |
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बोधानक: |
A1234.567 |
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प्रति 1 | उपलब्ध |