Inhibition of Osteoclast Differentiation by Carotenoid Derivatives through Inhibition of the NF-κB Pathway

• Main Authors: Shlomit Odes-Barth (Author), Marina Khanin (Author), Karin Linnewiel-Hermoni (Author), Yifat Miller (Author), Karina Abramov (Author), Joseph Levy (Author), Yoav Sharoni (Author)
• Format: Book
• Published: MDPI AG, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The bone protective effects of carotenoids have been demonstrated in several studies, and the inhibition of RANKL-induced osteoclast differentiation by lycopene has also been demonstrated. We previously reported that carotenoid oxidation products are the active mediators in the activation of the tra...