Mechanisms Underlying Pioglitazone-Mediated Relaxation in Isolated Blood Vessel

• Main Authors: Hidemi Nomura (Author), Hideyuki Yamawaki (Author), Masashi Mukohda (Author), Muneyoshi Okada (Author), Yukio Hara (Author)
• Format: Book
• Published: Elsevier, 2008-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pioglitazone is a widely used anti-type 2 diabetic drug. Beside its insulin-sensitizing effects, pioglitazone exerts preventive roles against ischemic heart disease. Since one possible explanation is anti-hypertensive action, we examined effects of pioglitazone on contractility of isolated blood ves...