Astragaloside IV ameliorates experimental autoimmune myasthenia gravis by regulating CD4 + T cells and altering gut microbiota

• Main Authors: Senhui Weng (Author), Linwen Huang (Author), Bingxing Cai (Author), Long He (Author), Shuting Wen (Author), Jinghao Li (Author), Zhuotai Zhong (Author), Haiyan Zhang (Author), Chongyang Huang (Author), Yunying Yang (Author), Qilong Jiang (Author), Fengbin Liu (Author)
• Format: Book
• Published: BMC, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Myasthenia gravis (MG) is an antibody-mediated autoimmune disease and its pathogenesis is closely related to CD4 + T cells. In recent years, gut microbiota is considered to play an important role in the pathogenesis of MG. Astragaloside IV (AS-IV) is one of the main active compon...