Toxicity Studies on Novel N-Substituted Bicyclo-Heptan-2-Amines at NMDA Receptors

• Главные авторы: Michelle Farbaniec (Автор), Adeboye Adejare (Автор), Shengguo Sun (Автор), Zeynep Ates-Alagoz (Автор), Boyenoh Gaye (Автор), Natalia Coleman (Автор)
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• Опубликовано: MDPI AG, 2013-04-01T00:00:00Z.
• Предметы: article
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Several novel norcamphor derivatives were designed and synthesized as uncompetitive NMDA receptor antagonists at the phencyclidine (PCP) binding site. Such compounds have potential as ligands for understanding and possibly the treatment of several neurodegenerative disorders and other glutamate-depe...