Diagnostic yield of targeted next-generation sequencing for pediatric hereditary hemolytic anemia

• Main Authors: Yu Jeong Choi (Author), Hongkyung Kim (Author), Won Kee Ahn (Author), Seung-Tae Lee (Author), Jung Woo Han (Author), Jong Rak Choi (Author), Chuhl Joo Lyu (Author), Seungmin Hahn (Author), Saeam Shin (Author)
• Format: Book
• Published: BMC, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Hereditary hemolytic anemia (HHA) refers to a heterogeneous group of genetic disorders that share one common feature: destruction of circulating red blood cells (RBCs). The destruction of RBCs may be due to membranopathies, enzymopathies, or hemoglobinopathies. Because these are...